Christopher Columbus (; between 25 August and 31 October 1451 – 20 May 1506) was an Italian explorer and navigator from the Republic of Genoa who completed four Spanish-based voyages across the Atlantic Ocean sponsored by the Catholic Monarchs, opening the way for the widespread European exploration and colonization of the Americas. His expeditions were the first known European contact with the Caribbean and Central and South America.

The name Christopher Columbus is the anglicisation of the Latin Christophorus Columbus. Growing up on the coast of Liguria, he went to sea at a young age and travelled widely, as far north as the British Isles and as far south as what is now Ghana. He married Portuguese noblewoman Filipa Moniz Perestrelo, who bore a son, Diego, and was based in Lisbon for several years. He later took a Castilian mistress, Beatriz Enríquez de Arana, who bore a son, Ferdinand.

Largely self-educated, Columbus was knowledgeable in geography, astronomy, and history. He developed a plan to seek a western sea passage to the East Indies, hoping to profit from the lucrative spice trade. After the Granada War, and Columbus's persistent lobbying in multiple kingdoms, the Catholic Monarchs, Queen Isabella I and King Ferdinand II, agreed to sponsor a journey west. Columbus left Castile in August 1492 with three ships and made landfall in the Americas on 12 October, ending the period of human habitation in the Americas now referred to as the pre-Columbian era.