The Manhattan Project was a research and development program undertaken during World War II to produce the first nuclear weapons. It was led by the United States in collaboration with the United Kingdom and Canada. From 1942 to 1946, the project was directed by Major General Leslie Groves of the U.S. Army Corps of Engineers. Nuclear physicist J. Robert Oppenheimer was the director of the Los Alamos Laboratory that designed the bombs. The Army program was designated the Manhattan District, as its first headquarters were in Manhattan; the name gradually superseded the official codename, Development of Substitute Materials, for the entire project. The project absorbed its earlier British counterpart, Tube Alloys, and subsumed the program from the American civilian Office of Scientific Research and Development. The Manhattan Project employed nearly 130,000 people at its peak and cost nearly US$2 billion (equivalent to about $27 billion in 2023), over 80 percent of which was for building and operating the plants that produced the fissile material. Research and production took place at more than 30 sites across the US, the UK, and Canada.

The project resulted in two types of atomic bombs, developed concurrently during the war: a relatively simple gun-type fission weapon and a more complex implosion-type nuclear weapon. The Thin Man gun-type design proved impractical to use with plutonium, so a simpler gun-type design called Little Boy was developed that used uranium-235.