OSIRIS-REx was a NASA asteroid-study and sample-return mission that visited and collected samples from 101955 Bennu, a carbonaceous near-Earth asteroid. The material, returned in September 2023, is expected to enable scientists to learn more about the formation and evolution of the Solar System, its initial stages of planet formation, and the source of organic compounds that led to the formation of life on Earth. Following the completion of the primary OSIRIS-REx (Regolith Explorer) mission, the spacecraft is planned to conduct a flyby of asteroid 99942 Apophis, now as OSIRIS-APEX (Apophis Explorer).

OSIRIS-REx was launched on 8 September 2016, flew past Earth on 22 September 2017, and rendezvoused with Bennu on 3 December 2018. It spent the next two years analyzing the surface to find a suitable site from which to extract a sample. On 20 October 2020, OSIRIS-REx touched down on Bennu and successfully collected a sample. OSIRIS-REx left Bennu on 10 May 2021 and returned its sample to Earth on 24 September 2023, subsequently starting its extended mission to study 99942 Apophis, where it will arrive in April 2029.

Bennu was chosen as the target of study because it is a "time capsule" from the birth of the Solar System. Bennu has a very dark surface and is classified as a B-type asteroid, a sub-type of the carbonaceous C-type asteroids. Such asteroids are considered primitive, having undergone little geological change from their time of formation.

101955 Bennu (provisional designation 1999 RQ₃₆) is a carbonaceous asteroid in the Apollo group discovered by the LINEAR Project on 11 September 1999. It is a potentially hazardous object that is listed on the Sentry Risk Table and has the highest cumulative rating on the Palermo Technical Impact Hazard Scale. It has a cumulative 1-in-1,750 chance of impacting Earth between 2178 and 2290 with the greatest risk being on 24 September 2182. It is named after Bennu, the ancient Egyptian mythological bird associated with the Sun, creation, and rebirth.

101955 Bennu has a mean diameter of 490 m (1,610 ft; 0.30 mi) and has been observed extensively by the Arecibo Observatory planetary radar and the Goldstone Deep Space Network.

Bennu was the target of the OSIRIS-REx mission that returned samples of the asteroid to Earth. The spacecraft, launched in September 2016, arrived at the asteroid two years later and mapped its surface in detail, seeking potential sample collection sites. Analysis of the orbits allowed calculation of Bennu's mass and its distribution. In October 2020, OSIRIS-REx briefly touched down and collected a sample of the asteroid's surface. A capsule containing the sample was returned and landed on Earth in September 2023, with distribution and analysis of the sample ongoing.